Result of Bortezomib Induction Therapy Prior to Stem Cell Transplantation in Newly Diagnosed Multiple Myeloma Cases in Mongolia

Authors

  • Khishigjargal Batsukh Center of Hematology and Bone Marrow Transplantation, First Central Hospital, Ulaanbaatar, Mongolia
  • Oyundelger Norov Center of Hematology and Bone Marrow Transplantation, First Central Hospital, Ulaanbaatar, Mongolia
  • Narangerel Jigjidkhorloo Center of Hematology and Bone Marrow Transplantation, First Central Hospital, Ulaanbaatar, Mongolia
  • Altanshagai Boldbaatar Center of Hematology and Bone Marrow Transplantation, First Central Hospital, Ulaanbaatar, Mongolia
  • Saruul Tungalag Center of Hematology and Bone Marrow Transplantation, First Central Hospital, Ulaanbaatar, Mongolia
  • Batbaatar Gunchin Mongolian National University of Medical Sciences; Ulaanbaatar, Mongolia
  • Odgerel Tsogbadrakh Division of Hematology, Department of Internal Medicine III, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia

DOI:

https://doi.org/10.24079/cajms.2017.06.011

Keywords:

Stem Cell, Transplantation, Bortezomib, Multiple Myeloma

Abstract

Objectives: For last 5 years, we have focused on establishing autologous stem cell transplantation (ASCT) in Mongolia. Herein, we report on three Mongolian multiple myeloma (MM) cases treated with bortezomib and dexamethasone (VD) prior to ASCT. Methods: The MM diagnosis was confirmed by bone marrow aspiration, urine protein electrophoresis, and serum protein electrophoresis. Results: Circulating white blood cells appeared 8-10 days after ASCT. Platelet levels recovered 10 -15 days after ASCT. Conclusion: In our MM cases, the VD regimen prior to ASCT obtained good response rates without the impairment of stem cells.

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Published

2017-06-25

How to Cite

Batsukh, K., Norov, O., Jigjidkhorloo, N., Boldbaatar, A., Tungalag, S., Gunchin, B., & Tsogbadrakh, O. (2017). Result of Bortezomib Induction Therapy Prior to Stem Cell Transplantation in Newly Diagnosed Multiple Myeloma Cases in Mongolia. Central Asian Journal of Medical Sciences, 3(2), 179–184. https://doi.org/10.24079/cajms.2017.06.011

Issue

Vol. 3 No. 2 (2017)

Section

Case Reports

License

Copyright (c) 2023 Mongolian National University of Medical Sciences

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