Хар мод /larix sibirica ldb./-ны мөчрийн боомын нян /bacillus anthracis/-гийн эсрэг идэвхит нэгдлийн судалгаа
DOI:
https://doi.org/10.5564/pmas.v51i199.835Keywords:
Larix sibirica Ldb, Bacillus anthracis, изопимарын хүчил,Abstract
No Mongolian Abstract
The methanol extract and its water nonsoluble fraction of the stem of Larix sibirica Ldb. exhibited a good inhibition activity against M.luteus strain and anthrax causal pathogen B.anthracis 90, 120, 147, 178 by the disc diffusion method. Activity-guided isolation of the water nonsoluble resin fraction led to the isolation of isopimaric acid which molecular structure was determined by 1H, 13C NMR spectroscopy and MS methods. Isopimaric acid exhibited a potential activity against M.luteus bacterial strain (9.5 mm) and B.anthracis 90 –17 mm, 120–15 mm, 147–15 mm, 178–17 mm, respectively.
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