The Effectiveness of Adjunctive Therapies Following Botulinum Toxin Type A Injections in Children with Cerebral Palsy

Authors

  • Narantsetseg Tsegmid Department of Rehabilitation Medicine, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia https://orcid.org/0000-0002-8132-0254
  • Delgerjargal Dorjbal Department of Rehabilitation Medicine, Fujita Health University, Toyoake, Japan
  • Nasantogtokh Erdenebileg National Center for Maternal and Child Health, Ulaanbaatar, Mongolia
  • Batchimeg Shirmen Department of Rehabilitation Medicine, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
  • Gerelmaa Zagd Department of Pediatric Medicine, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
  • Baljinnyam Avirmed Department of Rehabilitation Medicine, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia

DOI:

https://doi.org/10.24079/cajms.2023.03.002

Keywords:

Neurotoxin A, Rehabilitation, Electrical stimulation, Physiotherapy, Spasticit

Abstract

Objectives: To investigate the effectiveness of intermittent vs. continuous adjunctive therapies following BoNT-A injections for children with cerebral palsy (CP).
Methods: A quasi-experimental study was conducted with 80 participants with CP who received adjunctive therapies including physiotherapy and functional electrical stimulation after BoNT-A injections. The participants were randomly divided into two groups. In group A, half of the participants received intermittently adjunctive therapies. In group B, adjunctive therapies were organized continuously for another half. We measured changes in spasticity and dynamic spasticity used by the Modified Ashworth Scale and the Modified Tardieu Scale, and gross motor function used the Gross Motor Function Measure-88. Measurement of spasticity was carried out pre-injections and then 1- and 3-months post-injections. Measurement of gross motor function was organized pre- and post-injections.
Results: The effectiveness of BoNT-A injections presented significant improvement in spasticity and gross motor function when it was combined with adjunctive therapies. The continuous adjunctive therapies had a greater reduction of spasticity. Both intermittent and continuous adjunctive therapies had a significant improvement in gross motor function.
Conclusions: Our findings add to the evidence of the effectiveness of using different intervals of short-term adjunctive therapies for children with CP after BoNT-A injections.

Abstract
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Author Biographies

Narantsetseg Tsegmid, Department of Rehabilitation Medicine, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia

Mongolia-Japan hospital, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia

Batchimeg Shirmen, Department of Rehabilitation Medicine, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia

Mongolia-Japan hospital, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia

Baljinnyam Avirmed, Department of Rehabilitation Medicine, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia

Mongolia-Japan hospital, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia

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Published

2023-03-30

How to Cite

Tsegmid, N., Dorjbal, D., Erdenebileg, N., Shirmen, B., Zagd, G., & Avirmed, B. (2023). The Effectiveness of Adjunctive Therapies Following Botulinum Toxin Type A Injections in Children with Cerebral Palsy. Central Asian Journal of Medical Sciences, 9(1), 4–14. https://doi.org/10.24079/cajms.2023.03.002

Issue

Vol. 9 No. 1 (2023)

Section

Articles

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