Serum Lipid Profile and Its Association with Hypertension among Mongolian Adults

Abstract

Objective: The purpose of this study was to investigate the relationship between serum lipid profile and hypertension among Mongolian adults. Methods: This population-based cross-sectional study was conducted between January and June 2018 in Mongolia. According to current European Society of Cardiology guidelines, hypertension was defined as an average systolic blood pressure ≥140 mmHg and diastolic blood pressure ≥90 mmHg. Lipid profile (total cholesterol (TC), triglycerides (TG), high-density lipid [HDL], cholesterol and low-density lipid [LDL]-cholesterol) and fasting plasma glucose as well as Apolipoprotein B (ApoB), Apolipoprotein A (ApoA) and a ratio of apoB/apoA1 were estimated. Results: This study included 998 participants with a mean age ± SD of 49.4±14.8 years. Serum levels of TC, TG, and LDL were 4.8±0.93, 1.58±1.19 and 3.23±0.9 mmol/L, respectively among males, and 4.5±0.96, 1.22±0.48 and 2.95±1, respectively in females, which were significantly lower (p<0.05). The serum HDL was significantly lower (p<0.01) in males (1.67±0.22mmol/L) than in females (1.85±0.21). Conclusion: The results of this study demonstrate that people with hypertension are more likely have higher dyslipidemia, including elevated TC, TG, LDL and reduced HDL cholesterol level compared to a normotensive group. However, according to the binary logistic regression analysis, the most significant elevations of BP were attributed to age and reduced HDL.