Hair Growth Promoting Effect of Urticadioica L

Authors

  • Khaliun Myagmar Institute of Medical Sciences, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
  • Enkhsaikhan Lkhagvasuren Department of Microbiology and Immunology, School of Biomedicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia
  • Munkhbayar Semchin Institute of Medical Sciences, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia

DOI:

https://doi.org/10.24079/cajms.2018.09.004

Keywords:

Dermal Papilla Cells (hDPCs), Hair Follicle, Urdicadioica L, Ki-67

Abstract

Objectives: We investigated the effect of Urticadioica L extracts on hair growth by using in-vitro and ex vivo study methods. Methods: Human single hair follicle and dermal papilla cells obtained from scalp skin samples of healthy volunteers. We evaluated the effect of Urticadioica L on hDPCs and on ex vivo hair follicle organ culture. Hair follicle matrix cell’s proliferation marker Ki-67 identified by immunoflurescence staining. Results: Urticadioica L ethanol extracts promoted elongation of the hair shaft and reduced catagen transition of human hair follicles in organ culture model. E.extract of Urticadioica L increased Ki-67 positive matrix keratinocytes. Conclusions: Urticadioica L ethanol extract enhanced human hair growth in ex vivo organ culture model. Future study is needed related to its mechanism of hair growth.

Abstract
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Author Biography

Khaliun Myagmar, Institute of Medical Sciences, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia

Department of Microbiology and Immunology, School of Biomedicine, Mongolian National University of Medical Sciences, Ulaanbaatar, Mongolia

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Published

2018-09-25

How to Cite

Myagmar, K., Lkhagvasuren, E., & Semchin, M. (2018). Hair Growth Promoting Effect of Urticadioica L. Central Asian Journal of Medical Sciences, 4(3), 187–193. https://doi.org/10.24079/cajms.2018.09.004

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