Anatomical Region of the Colon as an Influencing Factor for Ulcerative Colitis Development

Abstract

Objectives: To determine if the anatomical location and extent of ulcerative inflammation influences the primary development of ulcerative colitis by defining the primary starting locations of ulcerative inflammation processes and determining the anatomical extents of ulcerative inflammation with the highest occurrence rates. Methods: A total of 152 patients were chosen during a period of two years. The diagnosis of ulcerative colitis was made by correlating clinical, endoscopic and histological features and data was retrospectively analyzed. Results: The group with the highest occurrence of ulcerative colitis was females aged 46-55. Out of the locations of terminal ileum cecum, ascending colon, transverse colon, descending colon, sigmoid colon and rectum, the sigmoid colon and rectum had the highest occurrence of inflammation. Out of cases in which one local part of the colon was affected, ascending and descending colon had zero cases, but the cecum, transverse colon, sigmoid colon, and rectum were affected. Conclusion: Ulcerative colitis is more commonly located at certain parts where the movements of colonic contents are decelerated, which warrants futher study about using bowel movement supporting medications for prevention and treatment of ulcerative colitis.