Seroprevalence of hepatitis e virus infection in some animals of Mongolia

Authors

  • Batmagnai Enkhbaatar Institute of Veterinary Medicine, MULS, 17024, Ulaanbaatar, Mongolia
  • Hagiwara Katsuro School of Veterinary Medicine, Rakunk-Gakuen University, 069-8501, Hokkaido, Japan
  • Boldbaatar Bazartseren School of Veterinary Medicine, MULS, 17024, Ulaanbaatar, Mongolia https://orcid.org/0000-0002-6137-7990

DOI:

https://doi.org/10.5564/mjas.v15i37.3098

Keywords:

pig, serological analysis, zoonosis, sheep, goats, cattle

Abstract

In order to analyze HEV seroprevalence in some animals of Mongolia, a total of 480 sera were collected from sheep, goats, cattle, horses, camels, and pigs raised in Tov, Dornogovi, and Selenge provinces. HEV zoonotic genotype 3 Virus Like Particle (VLP) protein was used in an indirect ELISA test as an antigen. A total of 68 animals, including 14 sheep, 15 goats, 4 cows, 1 horse, and 34 pigs, were diagnosed positive. The odds ratios of infection among species were high and statistically significant for pigs, sheep, and goats. Habitat and sex were statistically no significant. This study indicates that the risk of HEV infection is high among pigs, sheep, and goats in Mongolia. Nationwide comprehensive studies are needed to address food safety and public health issues in the future.

Монгол орны зарим мал, амьтдад элэгний е вирусийн халдварыг ийлдэс судлалын аргаар тандсан дүн

Хураангуй

Монгол орны зарим мал, амьтдад элэгний Е вирусийн (ЭЕВ) халдварыг тандах зорилгоор Төв, Дорноговь, Сэлэнгэ аймгуудаас хонь, ямаа, үхэр, адуу, тэмээ, гахайн нийт 480 ийлдэс цуглуулсан. Шууд бус ФХЭБУ-ын шинжилгээнд ЭЕВ-ын зооноз 3-р хэвшлийн VLP (вирус төст хэсэг) уургийг эсрэгтөрөгч болгон ашигласан. Үүнээс 14 хонь, 15 ямаа, 4 үхэр, 1 адуу, 34 гахай, нийт 68 толгой мал, амьтад ийлдэсний шинжилгээгээр эерэг гарсан. Зүйлүүдийн хувьд гахай, хонь, ямаа илүү өндөр халдвартай байсан бөгөөд статистикийн ач холбогдолтой байв. Амьдрах орчин, хүйсийн хувьд статистикийн ач холбогдолгүй байв. Энэхүү судалгаа нь манай орны гахай, хонь, ямаанд ЭЕВ-ын халдварын эрсдэл өндөр байгааг харуулж байна. Цаашид хүнсний аюулгүй байдал, нийгмийн эрүүл мэндийн асуудлыг шийдвэрлэхийн тулд улсын хэмжээнд цогц судалгаа хийх шаардлагатай байна.

Түлхүүр үг: гахай, ийлдэсний шинжилгээ, зооноз, хонь, ямаа, үхэр

Downloads

Download data is not yet available.
Abstract
54
PDF
40

References

R. H. Purcell and S. U. Emerson, “Hepatitis E: An emerging awareness of an old disease,” J. Hepatol., vol. 48, no. 3, pp. 494–503, 2008, https://doi.org/10.1016/j.jhep.2007.12.008

O.Baatarkhuu, G.Uugantsetseg, D.Munkhtsetseg et al., “Viral Hepatitis and Liver Diseases in Mongolia,” Euroasian J. Hepato-Gastroenterology, vol. 7, no. 1, pp. 68–72, 2017, https://doi.org/10.5005/jp-journals-10018-1215

S.Fukuda, M.Ishikawa, N.Ochiai et al., “Unchanged high prevalence of antibodies to hepatitis E virus (HEV) and HEV RNA among blood donors with an elevated alanine aminotransferase level in Japan during 1991-2006,” Arch. Virol., vol. 152, no. 9, pp. 1623–1635, 2007, https://doi.org/10.1007/s00705-007-0996-z

F.R.Lorenzo, B.Tsatsralt-Od, S.Ganbat, M.Takahashi, and H.Okamoto, “Analysis of the Full-Length Genome of Hepatitis E Virus Isolates Obtained From Farm Pigs in Mongolia,” J. Med. Virol., vol. 79, pp. 1128–1137, 2007, https://doi.org/10.1002/jmv.20905

B.Di Martino, F.Di Profio, I.Melegari et al., “Detection of hepatitis E virus (HEV) in goats,” Virus Res., vol. 225, pp. 69–72, 2016, https://doi.org/10.1016/j.virusres.2016.09.008

M.Demirci, A.Yiǧin, Ö.Ünlü, and S.K.Altun, “Detection of HEV RNA amounts and genotypes in raw milks obtained from different animals,” Mikrobiyol. Bul., vol. 53, no. 1, pp. 43–52, 2019, https://doi.org/10.5578/mb.67468

S. Li, M.Liu, J.Cong, Y.Zhou, and Z. Miao, “Detection and Characterization of Hepatitis e Virus in Goats at Slaughterhouse in Tai’an Region, China,” Biomed Res. Int., vol. 2017, no. March, 2017, https://doi.org/10.1155/2017/3723650

R. Dziedzinska, M. Krzyzankova, M. Bena, and P. Vasickova, “Evidence of hepatitis e virus in goat and sheep milk,” Viruses, vol. 12, no. 12, pp. 18–23, 2020, https://doi.org/10.3390/v12121429

H. S. Lee, D. T. Dao, V. N. Bui et al., “Prevalence and phylogenetic analysis of hepatitis e virus in pigs in Vietnam,” BMC Vet. Res., vol. 16, no. 1, pp. 1–10, 2020, https://doi.org/10.1186/s12917-020-02537-7

“World Health Organization. The Global Prevalence of Hepatitis E Virus Infection and Susceptibility: A Systematic Review,” World Heal. Organ. Geneva, Switz., vol. /IVB/10.14, 2010.

Y. Kanai, M. Tsujikawa, M. Yunoki, S. Nishiyama, K. Ikuta, and K. Hagiwara, “Long-Term Shedding of Hepatitis E Virus in the Feces of Pigs Infected Naturally, Born to Sows With and Without Maternal Antibodies,” J. Med. Virol., vol. 82, pp. 69–76, 2010, https://doi.org/10.1002/jmv.21647

V. Sarchese, F. Di Profio, I. Melegari et al., “Hepatitis E virus in sheep in Italy,” Transbound. Emerg. Dis., vol. 66, no. 3, pp. 1120–1125, 2019, https://doi.org/10.1111/tbed.13157

B. Yan, L. Zhang, L. Gong et al., “Hepatitis E virus in yellow cattle, Shandong, eastern China,” Emerg. Infect. Dis., vol. 22, no. 12, pp. 2211–2212, 2016, https://doi.org/10.3201/eid2212.160641

Downloads

Published

2022-12-30

How to Cite

Enkhbaatar, B. ., Katsuro, H. ., & Bazartseren, B. . (2022). Seroprevalence of hepatitis e virus infection in some animals of Mongolia. Mongolian Journal of Agricultural Sciences, 15(37), 73–78. https://doi.org/10.5564/mjas.v15i37.3098

Issue

Section

Articles